EndoMark

EndoMark

Project Overview

Year

About

EndoMark addresses delayed diagnosis by using menstrual blood to detect HMGB1, a biomarker linked to endometriosis. The simple lateral flow strip works like a pregnancy test, providing a clear positive or negative result in about fifteen minutes. By avoiding surgery and venous blood draws, it enables private self-screening and earlier referral to care. With sensitivity five times higher than standard lab methods, it could integrate with menstrual products and apps to broaden access and improve outcomes

Team

Nivetha Gunaseelan

Nivetha Gunaseelan

Nivetha Gunaseelan is a biomedical scientist and doctoral candidate at Pennsylvania State University, specializing in ultrasmall K-edge nanoparticles for early detection of traumatic diseases at the molecular level. As an American Heart Association predoctoral fellow, she has built several international collaborations to advance brain-injury detection and her work was recognized by European Foundation for Clinical Nanomedicine for translating novel nanomaterials into clinical probes. As a woman in STEM, Nivetha is also passionate about utilizing her research to advance women’s health. In 2024, she received the inaugural Dr. Barry Bercu Biomedical University Inventor Prize for inventing ‘EndoMark’ for early diagnosis of endometriosis.

Professor Dipanjan Pal

Professor Dipanjan Pal

Ketan Dighe

Ketan Dighe

Ketan Dighe is a biomedical scientist and doctoral candidate at Pennsylvania State University who specializes in point-of-care (POC) diagnostic platforms leveraging advanced nanomaterials. His cross-sector experience spanning academic research and industry collaborations has produced innovations ranging from rapid COVID-19 assays to next-generation diagnostics for sexually transmitted infections (STIs). Honored by the National Academy of Inventors, Ketan’s work advances accessible healthcare, particularly in women’s health, translating plasmonic and nanoscale materials into clinically significant tools. Central to his research is a translational approach: designing and refining technologies to close the gap from laboratory discovery to bedside care, accelerating patient access globally.

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